-dihydroxyphenyl rings of procyanidin C1 were being located in the construction mimicking K2E2·Pi condition. This interaction causes the ion pathway (that is formed by residues which include one of many interacting arginines, R979) to become inaccessible from your extracellular side76. This binding mode may Therefore sterically impede ion exchange. It https://le30021097.mdkblog.com/35294955/berzosertib-for-dummies