New selective PAD4 inhibitors binding a calcium-deficient form of the PAD4 enzyme have validated the critical enzymatic role of human and mouse PAD4 in both histone citrullination and neutrophil extracellular lure formation for, to our know-how, The very first time. The therapeutic possible of PAD4 inhibitors can now be explored. https://setherfrf.techionblog.com/40199101/gsk-484-hcl-secrets